Healthy dietary patterns and risk and survival of breast cancer: a meta‑analysis of cohort studies / Ruixue Hou, Jingkai Wei, Yirui Hu, Xiaotao Zhang, Xuezheng Sun, Eeshwar, Chandrasekar, Venkata Saroja Voruganti

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Bibliografía: p.843-846

Purposes Dietary patterns have been found to be associated with the overall cancer risk and survival. However, the associations of healthy dietary patterns and breast cancer remain unclear. We aimed to conduct a meta-analysis of prospective
cohort studies to estimate the pooled results of the association of healthy dietary patterns with breast cancer risk and survival.
Methods PubMed, EMBASE, and Web of Science were searched for literature published until June 24th, 2018 that examined
the associations between healthy dietary patterns and breast cancer risk and survival. Risk ratios (RRs) and 95% confdence
intervals (CIs) were calculated by using a random-efects model for meta-analysis.
Results There were 32 articles retrieved for the meta-analysis, with 27 for breast cancer risk and fve for breast cancer survival. There was a statistically signifcant lower risk of breast cancer associated with healthy dietary patterns (RR=0.93,
95% CI: 0.88, 0.98). Subgroup analysis results suggested that there was an inverse association between breast cancer risk
and posterori-derived healthy patterns, but no statistically signifcant associations were found in other stratifed subgroups
(a priori-derived diet, study region, menopausal status, or breast cancer subtypes). Healthy dietary patterns were associated
inversely with all-cause mortality (RR=0.76, 95% CI: 0.63, 0.92); however, no association was found for breast cancerspecifc mortality.
Conclusions The results suggested that healthy dietary patterns might be associated with a reduced risk of breast cancer
and all-cause mortality among breast cancer patients. It could be clinically relevant to promote healthy dietary patterns for
breast cancer prevention and improve survival among breast cancer patient