Congenital Cytomegalovirus Infection: Improved Understanding of Maternal Immune Responses That Reduce the Risk of Transplacental Transmission / Mark R. Schleiss
Material type:
Continuing resourceISSN: 1058-4838Subject(s): congenital cytomegalovirus | cytomegalovirus vaccine | cytomegalovirus screening | TORCH infection | placenta
In:
Clinical Infectious Diseases -- 2017, v. 65, 10, p. 1666-1669Summary: Congenital human cytomegalovirus (CMV) infection is a common cause of severe and permanent neurological injury in newborns. A meta-analysis concluded that congenital CMV infection occurs in approximately 0.65% of newborns in the United States [1]. The prevalence was similar when data from a prospective multicenter study was analyzed. This study of over 100,000 newborns identified congenital CMV infection in approximately 0.5% of all deliveries [2]. Of the 20000–30000 infants born in the United States
each year with congenital CMV, at least 10% will exhibit long-term neurodevelopmental sequelae, including mental retardation, seizure disorders, cerebral palsy, microcephaly, and sensorineural hearing loss [3]. The burden on society elicited by congenital CMV is substantial, and strategies to prevent infections in women of childbearing age are urgently needed
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Bibliografía: p. 1668-1669
Congenital human cytomegalovirus (CMV) infection is a common cause of severe and permanent neurological injury in newborns. A meta-analysis concluded that congenital CMV infection occurs in approximately 0.65% of newborns in the United States [1]. The prevalence was similar when data from a prospective multicenter study was analyzed. This study of over 100,000 newborns identified congenital CMV infection in approximately 0.5% of all deliveries [2]. Of the 20000–30000 infants born in the United States
each year with congenital CMV, at least 10% will exhibit long-term neurodevelopmental sequelae, including mental retardation, seizure disorders, cerebral palsy, microcephaly, and sensorineural hearing loss [3]. The burden on society elicited by congenital CMV is substantial, and strategies to prevent infections in women of childbearing age are urgently needed
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