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04631nas a22003977a 4500 |
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OSt |
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20210506163509.0 |
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ta |
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171219t2018 sp ||||| |||| 00| 0 spa | |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1138-7262 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
Salus Infirmorum |
| 245 00 - TITLE STATEMENT |
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| Title |
Neuropatía periférica producida por taxanos y calidad de vida global en pacientes con cáncer de mama = |
| Remainder of title |
Peripheral neuropathy caused by taxanes and overall quality of life in breast cancer patients / |
| Statement of responsibility, etc. |
Arianna Rosich Soteras, Ana Belén Rodríguez, Laia Paré Brunet, Anna Serrahima Mackay |
| 500 ## - GENERAL NOTE |
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| General note |
Este artículo se encuentra disponible en su edición impresa. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Bibliografía: p.73 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Objetivo: determinar la incidencia y evolución de la neuropatía periférica inducida por taxanos (NPIT) en pacientes con cáncer de mama y valorar la influencia de la NPIT en la calidad de vida global (CV).Método: estudio descriptivo longitudinal prospectivo realizado en el Servicio de Oncología del Hospital Clínic de Barcelona (julio 2015-abril 2016). Se incluyeron mujeres diagnosticadas de cáncer de mama en su primera línea de tratamiento con quimioterapia (paclitaxel o docetaxel) en quienes se evaluó la neurotoxicidad y la calidad de vida mediante tres cuestionarios autoinformados validados al inicio, a las 6 y 12 semanas y un mes tras finalizar el tratamiento.Resultados: participaron 33 pacientes de las cuales el 84,4% había desarrollado algún grado de NP al final del seguimiento. La neurotoxicidad empeoró de manera estadísticamente significativa con la acumulación de dosis hasta el final del tratamiento y se mantuvo estable un mes tras la última administración (p< 0,001). La neuropatía sensitiva aumentó de manera estadísticamente significativa a lo largo del seguimiento (p< 0,001). La afectación de la sensibilidad motora también, salvo en la última medición (p< 0,005). Se observó una correlación positiva entre la neurotoxicidad y deterioro de la CV (r= 0,609 (p< 0,0001))Conclusiones: la NPIT es un efecto secundario con una alta incidencia en la población de mujeres con cáncer de mama estudiada y provoca un efecto negativo en la CV percibida de las pacientes. Las enfermeras oncológicas son profesionales clave en la prevención y el manejo de este efecto secundario. |
| 520 8# - SUMMARY, ETC. |
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| Summary, etc. |
Objective: to determine the incidence and evolution of taxane-induced peripheral neuropathy (TIPN) in breast cancer patients, and to assess the influence of TIPN on overall quality of life (QoL). Method: a prospective longitudinal descriptive study conducted at the Oncology Unit of the Hospital Clínic de Barcelona (July, 2015- April, 2016). The study included women with diagnosis of breast cancer, on their first line of treatment with chemotherapy (paclitaxel or docetaxel); neurotoxicity and quality of life were evaluated through three self-reported questionnaires validated at baseline, at 6 and 12 weeks, and one month after completing treatment. Results: the study included 33 patients; 84.4% of them had developed some degree of PN at the end of follow-up. There was a statistically significant worsening in neurotoxicity with dose accumulation until the end of the treatment, and it remained stable one month after the last administration (p< 0.001). There was a statistically significant increase in sensitive neuropathy throughout follow-up (p< 0.001); also in terms of involvement in motor sensitivity, except in the final measurement (p< 0-005). A positive correlation was observed between neurotoxicity and QoL deterioration (r= 0.609 (p<0.0001)). Conclusions: TIPN is a side effect with high incidence among the population studied of women with breast cancer, and it causes a negative impact on patient-perceived QoL. Oncology nurses are the key professionals for the prevention and management of this side effect. |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Neuropatía periférica inducida por taxanos |
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| Uncontrolled term |
calidad de vida |
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| Uncontrolled term |
taxoides |
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| Uncontrolled term |
neuropatía |
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| Uncontrolled term |
síndromes de neurotoxicidad |
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| Uncontrolled term |
medición de resultados informados por el paciente |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
control de síntomas |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
estudio descriptivo longitudinal |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Taxane-induced peripheral neuropathy |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
quality of life |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
taxoids |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
neuropathy |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
neurotoxicity syndromes |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
measurement of patient-reported results |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
symptom control |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
longitudinal descriptive study |
| 773 ## - HOST ITEM ENTRY |
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| Related parts |
-- 2018 (abr), v. 21, n. 3, p. 67-73 |
| Title |
Metas de enfermería. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Universal Decimal Classification |
| Koha item type |
Artículo de revista |
