000			02292nas a22001817a 4500
003			OSt
005			20230504095329.0
006			m|||||r|||| 00| 0
007			ta
008			171219t2011 sp ||||| |||| 00| 0 spa |
022			_a1055-9965
040			_cSalus Infirmorum
245	0		_aSucrose, High-Sugar Foods, and Risk of Endometrial Cancer. A Population-Based Cohort Study / _cEmilie Friberg, Alice Wallin, and Alicja Wolk
504			_aBibliografía: p.1836-1837
520	8		_aBackground: Consumption of high-sugar foods stimulates insulin production, which has been associated with endometrial cancer. Although a relationship between sucrose, high-sugar food consumption, and endometrial cancer risk is biologically plausible, this hypothesis has previously been explored in very few studies. Methods: We used data from the Swedish Mammography Cohort, including 61,226 women aged 40 to 74 years. We examined the association between consumption of total sucrose, high-sugar foods (at baseline 1987–1990 and 1997) and endometrial cancer risk by using Cox proportional hazards models to estimate incidence rate ratios (RR) with 95% CI. Results: During 18.4 years of follow-up, 729 participants were diagnosed with incident endometrial cancer. Total sucrose intake and consumption of sweet buns and cookies was associated with increased risk of endometrial cancer. RRs (with 95% CIs) for consuming more than 35 grams of sucrose per day and consuming sweet buns and cookies more than 3 times per week were 1.36 (1.04–1.77) and 1.42 (1.15–1.75) as compared with less than 15 grams of sucrose per day and consuming sweet buns and cookies less than 0.5 times per week, respectively. RRs for consuming more than 15 grams of sucrose per day as compared with 15 grams or less were 1.97 (1.27–3.04) among obese women and 1.56 (1.20–2.04) among women with low fat intake. Conclusions: These data indicate that sucrose intake and consumption of sweet buns and cookies may be associated with increased risk of endometrial cancer. Impact: Given the high intake of sweetened foods, these results have public health implications in terms of prevention of endometrial cancer
773			_g-- 2011 v. 20, n 9, p.1831-1837 _tCancer Epidemiology, Biomarkers & Prevention
942			_2udc _cARTÍCULO
999			_c15057 _d15057