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022			_a1462-3994
040			_cSalus Infirmorum
245	0	3	_aEndometriosis : _bdisease pathophysiology and the role of prostaglandins / _cMeng-Hsing Wu, Yutaka Shoji, Pei-Chin Chuang and Shaw-Jenq Tsai
500			_aEste artículo se encuentra disponible en su edición impresa.
504			_aBibliografía: p.15-19
520	8		_aEndometriosis is considered to be a polygenic disease with a complex, multifactorial aetiology that affects about 10% of women in the reproductive age. Women with endometriosis have symptoms that include chronic pelvic pain, dysmenorrhoea and dyspareunia, significantly reducing their quality of life. Endometriosis is also the primary cause of infertility in women, with the prevalence rate ranging from 20% to 50%. The high prevalence and severe outcomes of this disease have made it a major public health concern in modern society. Currently, the mechanism(s) responsible for the initiation and promotion of this disease remains obscure. In this review, we focus on the expression, regulation and action of prostaglandins in the cellular and molecular mechanisms that contribute to the development and/or maintenance of endometriosis.
773			_g-- 2007 v. 9, n.2, p.1-16 _tExpert Reviews in Molecular Medicine
942			_2udc _cARTÍCULO
999			_c14867 _d14867