The English Version of the Gilles de la Tourette Syndrome–Quality of Life Scale for Children and Adolescents (C&A-GTS-QOL): A Validation Study in the United Kingdom / Merina T. Su, Fiona McFarlane, Andrea E. Cavanna, Cristiano Termine, Imogen Murray, Larissa Heidemeyer, Isobel Heyman, Tara Murphy

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Bibliografía: p.82-83

Gilles de la Tourette syndrome is a chronic neuropsychiatric disorder that can have a detrimental impact on the health-related
quality of life of children with the condition. To date no patient-reported health-related quality of life measures have been
developed for children and adolescents in the English language. This study validated the first disease-specific scale for the
quantitative assessment of health-related quality of life in 118 children and adolescents with Gilles de la Tourette syndrome (C&AGTS-QOL) following language adaptation from Italian to English in the United Kingdom. Standard statistical methods were used to
test the psychometric properties of the rating scale. Principal component factor analyses led to the identification of six healthrelated quality of life domains (cognitive, copro-phenomena, psychological, physical, obsessive-compulsive, and activities of daily
living), explaining 66.7% of the overall variance. The C&A-GTS-QOL demonstrated satisfactory scaling assumptions and
acceptability; validity was supported by interscale correlations (range 0.2-0.7), confirmatory factor analysis, and correlation
patterns with other rating scales and clinical variables.