Facultad de Enfermería y Fisioterapia Salus Infirmorum

Heat-killed Lactobacillus helveticus improves mood states: a randomised, double-blind, placebo-controlled study / (Record no. 15318)

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control field 20250130161000.0
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International Standard Serial Number 1876-2883
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Transcribing agency Salus Infirmorum
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Title Heat-killed Lactobacillus helveticus improves mood states: a randomised, double-blind, placebo-controlled study /
Statement of responsibility, etc. N. Mutoh, I. Kakiuchi, A. Hiraku, N. Iwabuchi, K. Kiyosawa, K. Igarashi, M. Tanaka, M. Nakamura and M. Miyasaka
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Bibliography, etc. note Bibliografía: p 116-117
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Summary, etc. We investigated the effects of heat-killed Lactobacillus helveticus MCC1848 on daily mood states in healthy young adults. Participants (n=58) were randomised to receive heat-killed L. helveticus MCC1848 powder or placebo powder for 4 weeks. During the study period, adverse events were recorded in the participant diary. Mood states were assessed before and 2 and 4 weeks after initiation of the intervention. The primary outcomes were the shortened version of the Profile of Mood States 2 (POMS 2) scores. Secondary outcomes included other mood state (State-Trait Anxiety Inventory (STAI); visual analogue scale (VAS)), quality of life (acute form of the SF-36v2), sleep (Athens Insomnia Scale (AIS)) and fatigue (Chalder Fatigue Scale (CFS)) scores. Four weeks of heat-killed L. helveticus MCC1848 intake, compared to placebo, significantly improved the shortened version of the POMS 2 ‘friendliness’ and the VAS ‘relaxed’ scores, which are two indicators of positive mood states. On the other hand, heat-killed L. helveticus MCC1848 intake had no significant effects on negative mood state items (e.g. anger, nervousness, confusion) assessed by the shortened version of the POMS 2, STAI and VAS. AIS and CFS scores also showed no significant differences. No adverse effects were observed with 4 weeks of heat-killed L. helveticus MCC1848 intake.<br/>These results suggest that daily consumption of heat-killed L. helveticus MCC1848 is safe and has the potential to improve positive mood states.
653 14 - INDEX TERM--UNCONTROLLED
Uncontrolled term gut-brain axis
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Uncontrolled term psychobiotics
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Uncontrolled term psychological stress
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Related parts -- 2023, v. 14, n 2, p.109-117
Title BENEFICIAL MICROBES
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Source of classification or shelving scheme Universal Decimal Classification
Koha item type Artículo de revista
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection code Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    Universal Decimal Classification     Non-fiction Revistas y artículos Revistas y artículos 30/01/2025   PP 6278 30/01/2025 30/01/2025 Artículo de revista

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