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02906nas a22002417a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20250130121322.0 |
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ta |
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171219t2023 sp ||||| |||| 00| 0 spa | |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1051-2276 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
Salus Infirmorum |
| 245 0# - TITLE STATEMENT |
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| Title |
Short-Term Effects of a Therapeutic Diet on Biochemical Parameters in Hemodialysis Patients: A Randomized Crossover Trial / |
| Statement of responsibility, etc. |
Wan-Chuan Tsai, Shih-Ping Hsu, Yen-Ling Chiu, Hon-Yen Wu, Chia-Chin Luan, Ju-Yeh Yang Mei-Fen Pai, Cheng-Jui Lin, Wan-Yu Lin Wen-Huei Sun, and Yu-Sen Peng<br/><br/> |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Bibliografía: p 739 |
| 520 8# - SUMMARY, ETC. |
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| Summary, etc. |
Objective: Although unhealthy diets exacerbate nutritional and metabolic derangements in patients with end-stage kidney disease<br/>(ESKD), how therapeutic diets that possess a variety of different dietary strategies acutely modify diverse biochemical parameters<br/>related to cardiovascular disease remains underexplored.<br/>Methods: Thirty-three adults with end-stage kidney disease undergoing thrice-weekly hemodialysis participated in a randomized<br/>crossover trial comparing a therapeutic diet with their usual diets for 7 days, separated by a 4-week washout period. The therapeutic<br/>diet was characterized by adequate calorie and protein amounts, natural food ingredients with a low phosphorus-to-protein ratio, higher<br/>portions of plant-based food, and high fiber content. The primary outcome measure was the mean difference in the change-from-<br/>baseline intact fibroblast growth factor 23 (FGF23) level between the 2 diets. The other outcomes of interest included changes in mineral<br/>parameters, uremic toxins, and high-sensitivity C-reactive protein (hs-CRP) levels.<br/>Results: Compared with the usual diet, the therapeutic diet lowered intact FGF23 levels (P 5 .001), decreased serum phosphate<br/>levels (P , .001), reduced intact parathyroid hormone (PTH) levels (P 5 .003), lowered C-terminal FGF23 levels (P 5 .03), increased<br/>serum calcium levels (P 5 .01), and tended to lower total indoxyl sulfate levels (P 5 .07) but had no significant effect on hs-CRP levels.<br/>Among these changes, reduction in serum phosphate level achieved in 2 days, modifications of intact PTH and calcium levels in 5 days,<br/>and reductions in intact and C-terminal FGF23 levels in 7 days of therapeutic diet intervention.<br/>Conclusion: Within the 1-week intervention period, the dialysis-specific therapeutic diet rapidly reversed mineral abnormalities and<br/>tended to decrease total indoxyl sulfate levels in patients undergoing hemodialysis but had no effect on inflammation. Future studies to<br/>assess the long-term effects of such therapeutic diets are recommended.<br/> |
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| Uncontrolled term |
dialysis |
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| Uncontrolled term |
FGF23 |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
inflammation |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
therapeutic diet |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
uremic toxin |
| 773 ## - HOST ITEM ENTRY |
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| Related parts |
-- 2023, v. 33, n 6, p.731-739 |
| Title |
Journal of Renal Nutrition |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Universal Decimal Classification |
| Koha item type |
Artículo de revista |
