MARC details
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02826nas a22002537a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20220530161545.0 |
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| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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ta |
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171219t2018 sp ||||| |||| 00| 0 spa | |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1526-8209 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
Salus Infirmorum |
| 245 00 - TITLE STATEMENT |
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| Title |
Physical Activity and Weight Loss Reduce the Risk of Breast Cancer: A Meta-analysis of 139 Prospective and Retrospective Studies / |
| Statement of responsibility, etc. |
Prue J. Hardefeldt, Ross Penninkilampi, Senarath Edirimanne, Guy D. Eslick |
| 500 ## - GENERAL NOTE |
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| General note |
PDF en biblioteca |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Bibliografía: p.e609-e612 |
| 520 8# - SUMMARY, ETC. |
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| Summary, etc. |
The aim of this meta-analysis was to assess the effect of both physical activity and weight loss on breast cancer incidence. A total of 139 studies were included, involving 236,955 cases and 3,963,367 controls. Physical activity significantly reduced the risk of breast cancer (odds ratio, 0.78; P < .001). The effect size was similar in pre- and postmenopausal women. High-intensity physical exercise was slightly more protective.<br/>Background: Physical activity and weight loss have been shown to reduce breast cancer incidence in numerous observational studies. The aim of this meta-analysis was to assess the effect of both physical activity and weight loss on breast cancer incidence. Specifically, we aimed to complete subgroup analyses by the intensity of physical activity and menopausal status at breast cancer diagnosis to further elucidate the relationship between physical activity, weight loss, and breast cancer incidence. Materials and Methods: Studies were obtained from a database search of MEDLINE, EMBASE, PubMed, Current Contents Connect, and Google Scholar through November 5, 2017. A randomeffects model was used for pooled data. Results: There were 139 studies included in the meta-analysis, including<br/>236,955 cases and 3,963,367 controls. Physical activity significantly reduced the risk of breast cancer (odds ratio [OR], 0.78; 95% confidence interval [CI], 0.76-0.81; P < .001), with high-intensity physical activity being slightly more protective (OR, 0.73; 95% CI, 0.65-0.81; P < .001) than low-intensity exercise (OR, 0.79; 95% CI, 0.72-0.86; P < .001).<br/>The effect size for general exercise was similar in both premenopausal (OR, 0.79; 95% CI, 0.73-0.87; P < .001) and postmenopausal (OR, 0.82; 95% CI, 0.78-0.86; P < .001) women. Additionally, weight loss reduced the risk of breast cancer incidence (OR, 0.82; 95% CI, 0.67-0.97). Conclusion: Physical activity and weight loss significantly reduce the risk of breast cancer, irrespective of the timing and intensity of the exercise. |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
body mass index |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
exercise |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
menopause |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
review |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
risk factors |
| 773 ## - HOST ITEM ENTRY |
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| Related parts |
-- 2018, v. 18, n4, p. e601-e612 |
| Title |
Clinical Breast Cancer |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Universal Decimal Classification |
| Koha item type |
Artículo de revista |
