MARC details
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02336nas a22002417a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20220530141954.0 |
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| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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ta |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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171219t2018 sp ||||| |||| 00| 0 spa | |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0167-6806 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
Salus Infirmorum |
| 245 00 - TITLE STATEMENT |
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| Title |
Menopausal hormone therapy and the risk of breast cancer by histological type and race: a meta‑analysis of randomized controlled trials and cohort studies / |
| Statement of responsibility, etc. |
Sohyun Kim, Yeonsook Ko, Hwa Jeong Lee, Jung‑eun Lim<br/> |
| 500 ## - GENERAL NOTE |
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| General note |
PDF en biblioteca |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Bibliografía: p.674-675 |
| 520 8# - SUMMARY, ETC. |
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| Summary, etc. |
Purpose This meta-analysis investigated the association between the risk of breast cancer and hormone replacement therapy (HRT). Various stratifed analyses were performed according to race (Asian/Westerner), HRT type [all hormone therapies, estrogen-only therapy (ET), or combined estrogen–progestin therapy (EPT)], histological breast cancer type (ductal/lobular/mixed ductal–lobular), and estrogen receptor status (ER-positive/ER-negative).<br/>Methods A literature search was performed using Pubmed, Embase, and KoreaMed. Twenty-fve epidemiological studies including 23 cohort studies and two randomized controlled trials were included in this meta-analysis.<br/>Results Using a random-efects model, HRT use was found to be positively associated with the risk of breast cancer with a pooled hazard ratio (HR) of 1.33 [95% confdence interval (CI) 1.24, 1.44]. Compared with ET, EPT was more strongly associated with breast cancer risk. EPT was associated with both ductal and lobular breast cancer risks [for ductal breast cancer, HR=1.51 (95% CI 1.28, 1.78); for lobular breast cancer, HR=1.38 (95% CI 1.20, 1.60)]. According to ER status, all HRTs were associated with the risk of ER-positive breast cancer, but not with that of ER-negative breast cancer.<br/>Conclusions Asian HRT users had a higher risk of breast cancer than western HRT users. Both ET and EPT were signifcantly associated with the risk of all breast cancer histological types and ER-positive breast cancer |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
breast cancer |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
menopausal hormone therapy |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
hormone replacement therapy |
| 653 14 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
meta-analysis |
| 773 ## - HOST ITEM ENTRY |
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| Related parts |
-- 2018, v. 170, n3, p. 667–675 |
| Title |
Breast Cancer Research and Treatment |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Universal Decimal Classification |
| Koha item type |
Artículo de revista |
