Assessing the risk to health care staff from long-term exposure to anticancer drugs – the case of monoclonal antibodies / (Record no. 13184)
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| fixed length control field | 02077nas a22002537a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20210608124531.0 |
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| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
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| fixed length control field | 171219t2011 sp ||||| |||| 00| 0 spa | |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1477-092X |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | Salus Infirmorum |
| 245 00 - TITLE STATEMENT | |
| Title | Assessing the risk to health care staff from long-term exposure to anticancer drugs – the case of monoclonal antibodies / |
| Statement of responsibility, etc. | Gabriele Halsen, Irene Krämer |
| 500 ## - GENERAL NOTE | |
| General note | PDF en biblioteca |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliografía: p.78-80 |
| 520 8# - SUMMARY, ETC. | |
| Summary, etc. | Today the occupational health and safety risk involved when handling most anticancer drugs is well recognized<br/>and, as a result of regulatory requirements, safety measures have been established. There is little knowledge<br/>about the occupational hazard posed by handling monoclonal antibodies assigned to ATC Class L01XC. The aim of<br/>our study was to evaluate the occupational risk of monoclonal antibodies. Using the information obtained in a systematic<br/>review of the literature, the potentially dangerous properties of the active drug substances were assessed using<br/>a specially devised algorithm. As a result, all monoclonal antibodies in question were categorized as substances<br/>with developmental toxicity. In addition, gemtuzumab ozogamicin was categorized as mutagenic. In view of the high<br/>molecular weights and the proteinogenic nature of monoclonal antibodies, the route of exposure for health care staff<br/>is limited to inhalation, unless there is an accident. Employers should implement the necessary administrative and<br/>engineering controls. Employees should adhere to the standards in order to avoid occupational exposure. The hazard<br/>assessment algorithm devised and the evaluation procedure may also be used for other drugs considered to be<br/>dangerous. |
| 653 14 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | monoclonal antibodies |
| 653 14 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ATC Class L01XC |
| 653 14 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | occupational exposure |
| 653 14 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | risk assessment |
| 653 14 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | occupational hazard |
| 773 ## - HOST ITEM ENTRY | |
| Related parts | -- 2011, v. 17, 1, p. 68-80 |
| Title | Journal of oncology pharmacy practice |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Universal Decimal Classification |
| Koha item type | Artículo de revista |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Universal Decimal Classification | Non-fiction | Revistas y artículos | Revistas y artículos | 08/06/2021 | PP | 5795 | 08/06/2021 | 08/06/2021 | Artículo de revista |