Influence of Parental Exposure to Risk Factors in the Occurrence of Oral Clefts / (Record no. 13087)
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control field | OSt |
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control field | 20210406154859.0 |
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007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
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fixed length control field | 171219t2020 sp ||||| |||| 00| 0 spa | |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
International Standard Serial Number | 0300-5712 |
040 ## - CATALOGING SOURCE | |
Transcribing agency | Salus Infirmorum |
245 00 - TITLE STATEMENT | |
Title | Influence of Parental Exposure to Risk Factors in the Occurrence of Oral Clefts / |
Statement of responsibility, etc. | Sandra Regina Altoé, Álvaro Henrique Borges, Ana Thereza de Saboia Campos Neves, Andreza Maria Fábio Aranha, Alexandre Meireles Borba, Mariano Martinez Espinosa,Luiz Evaristo Ricci Volpato |
500 ## - GENERAL NOTE | |
General note | PDF en biblioteca |
504 ## - BIBLIOGRAPHY, ETC. NOTE | |
Bibliography, etc. note | Bibliografía: 125-126 |
520 8# - SUMMARY, ETC. | |
Summary, etc. | Statement of the Problem: Non-syndromic cleft lip and palate are the most frequent craniofacial abnormalities in humans. The genetic, environmental and behavioral factors involved in this malformation must be clarified in different parts of the globe in the view of implementing preventive measures.<br/>Purpose: To analyze the influence of parental exposure to risk factors on the occurrence of oral clefts.<br/>Materials and Method: A case-control study was conducted with 150 mothers of oral cleft children paired by the children’s gender to 300 mothers of children without congenital anomalies from Mato Grosso, Brazil, for the study of the variables: gender and race/color of the children; parental educational level; age; number of pregnancies; prenatal care; obesity; stress; diabetes; hypertension; use of medications, alcohol and illicit drugs; smoking and exposure to ionizing radiation during the first trimester of pregnancy. The results were analyzed in relation to the chances possibility of each variable for the occurrence of oral cleft through the bivariate and multivariate analysis by applying the model of logistic regression.<br/>Results: Passive smoking, obesity, exposure to ionizing radiation and use of antibiotics were associated with the presence of clefts. The use of folic acid and analgesics were identified as preventive factors. The father's low educational level was found as a risk factor, while the black race/color was a preventive factor; nevertheless these variables were not associated in the multivariate analysis.<br/>Conclusion: The results reinforce the need to follow up the pregnant women, especially in the first trimester of pregnancy, in order to control the identified risk factors. Considering the factors associated with occurrence of oral clefts and those associated with its prevention, it is possible to apply specific health promotion measures during pregnancy, which can result in the reduction of oral clefts’ occurrence. |
653 14 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Case-Control Studies |
653 14 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Cleft Lip |
653 14 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Cleft Palate |
653 14 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Risk Factors |
773 ## - HOST ITEM ENTRY | |
Related parts | -- 2020, v. 21, 2, p. 119-126 |
Title | Journal of Dentistry |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Universal Decimal Classification |
Koha item type | Artículo de revista |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
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Universal Decimal Classification | Non-fiction | Revistas y artículos | Revistas y artículos | 06/04/2021 | PP | 5730 | 06/04/2021 | 06/04/2021 | Artículo de revista |