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000 -LEADER |
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02390nas a22001937a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
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OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
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20210316120336.0 |
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007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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171219t2020 sp ||||| |||| 00| 0 spa | |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1559-047X |
040 ## - CATALOGING SOURCE |
Transcribing agency |
Salus Infirmorum |
245 00 - TITLE STATEMENT |
Title |
Incidence and Prognostic Value of Acute Coagulopathy After Extensive Severe Burns / |
Statement of responsibility, etc. |
Kang Geng, Yonglin Liu, Yuting Yang, MS, Xiaobin Ding, Xinli Tian, Hongjun Liu, Hong Yan |
500 ## - GENERAL NOTE |
General note |
Este artículo se encuentra disponible en su edición impresa. |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc. note |
Bibliografía: p.549 |
520 8# - SUMMARY, ETC. |
Summary, etc. |
Acute burn-induced coagulopathy (ABIC) occurs after severe burns. However, the incidence, prognostic value, and clinical significance of ABIC after an extensive severe burn remain inconclusive due to wide variances in burn severity and coagulation profile evaluation timings in previous studies. This retrospective study explored the incidence and clinical and prognostic significance of early phase ABIC in 129 adult patients with extensive burns (>50% total body surface area [TBSA]) admitted to the burn centers of two hospitals within 10 hours postburn injury during 2009–2017. Demographics (age and sex) and clinical data (burn severity, vital signs, prehospital fluid replacement volume, hemodynamic parameters, coagulation profile, blood gas,<br/>and blood biochemical indicators) were collected upon admission. The incidence of ABIC in patients with severe burns and its relationship with their survival and clinical significance were analyzed. The average postburn interval was 5.7 ± 2.7 hours, and the incidence of ABIC was 31% (40/129). A logistic regression analysis identified ABIC as an independent predictor of 4-week severe mortality due to severe burn. The incidence of ABIC was significantly associated with the total burn area, lactic acid levels upon admission, and postburn admission interval, but not with the prehospital fluid replacement volume. In conclusion, approximately 30% of patients with severe burns developed ABIC within 10 hours postburn, and this condition strongly predicts 4-week mortality. Although burn severity and tissue ischemia/hypoxia are main risk factors for ABIC, the pathogenesis is not fully understood and should be explored in future studies. |
773 ## - HOST ITEM ENTRY |
Related parts |
-- 2020, v. 41, n. 3, p. 544-549 |
Title |
Journal of Burn Care and Research |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Universal Decimal Classification |
Koha item type |
Artículo de revista |